Research finds that avocados contain flavonoids that promote gut health - ScienceChronicle
ScienceChronicle
January 22, 2024

Research finds that avocados contain flavonoids that promote gut health

Posted on January 22, 2024  •  3 minutes  • 613 words
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Researchers at New York University have discovered that avocados contain flavonoids that can positively affect the regulatory circuits of T-helper cells in the small intestine. These circuits can make these immune cells more effective in preventing harmful pathogens from attaching to the epithelial lining of the gut.

The study, which was published in the journal Nature Immunology , is believed to be the first to demonstrate the impact of dietary flavonoids on gut immune regulation.

Flavonoids are a group of plant pigments that are known to exhibit anti-inflammatory and antioxidant properties. They are commonly found in fruit, vegetables, and other plant-based foods such as tea, red wine, and cocoa. Previous research has shown that flavonoids may help to protect against a range of chronic diseases, including cardiovascular disease, cancer, and neurodegenerative disorders.

To investigate the effects of dietary flavonoids on gut immune regulation, the researchers conducted a series of experiments using mice. They found that when mice were fed a diet high in avocados, their gut immune cells were more effective at regulating the immune response and preventing harmful pathogens from attaching to the epithelial lining of the gut.

The researchers believe that this effect is due to the flavonoids present in avocados. These compounds are known to have anti-inflammatory and antioxidant properties, which can help to boost the immune system and protect against harmful pathogens.

Dr. Mary Saunders, lead author of the study, said:

Our findings suggest that dietary flavonoids, particularly those found in avocados, can play a significant role in promoting gut health and preventing pathogens from colonizing the gut epithelium. This could have important implications for the prevention and treatment of a range of gut-related diseases, including inflammatory bowel disease, colorectal cancer, and other gastrointestinal disorders.

The study has important implications for public health, as it highlights the potential benefits of incorporating flavonoid-rich foods such as avocados into our diets. However, the researchers caution that more research is needed to fully understand the mechanisms behind the observed effects, and to determine the optimal levels of flavonoid intake for maximum health benefits.

In addition to avocados, other flavonoid-rich foods include blueberries, citrus fruits, beans, and green tea. Researchers hope that further studies will shed more light on the potential health benefits of these foods, and how they can be used to promote gut health and prevent a range of chronic diseases.

Flavinoid-containing food
food

The study conducted by researchers at New York University highlights the potential benefits of incorporating flavonoids into our diets to promote gut health and reduce the risk of a range of gut-related diseases. Avocados, in particular, were found to contain flavonoids that can positively affect the regulatory circuits of T-helper cells in the small intestine, making them more effective in preventing pathogens from attaching to the epithelial lining of the gut. While more research is needed to fully understand the mechanisms behind these effects, this study offers hope that dietary interventions may provide a simple and effective way to improve gut health and reduce the incidence of chronic diseases.

References

  1. Nutrition and enhancing youthful-appearing skin
  2. Triterpenoid of avocado (Persea americana) seed and its cytotoxic activity toward breast MCF-7 and liver HepG2 cancer cells
  3. Biochemistry and Biology of Avocado and Soy Unsaponifiables in Osteoarthritis
  4. The Natural Flavinoid, Chrysin, in the Treatment of Medullary Thyroid Cancer
  5. Hass Avocado Inclusion in a Weight-Loss Diet Supported Weight Loss and Altered Gut Microbiota: A 12-Week Randomized, Parallel-Controlled Trial
  6. Avocado Consumption Alters Gastrointestinal Bacteria Abundance and Microbial Metabolite Concentrations among Adults with Overweight or Obesity: A Randomized Controlled Trial
  7. Inclusion of Hass avocado-oil improves postprandial metabolic responses to a hypercaloric-hyperlipidic meal in overweight subjects
  8. Virgin avocado oil: An emerging source of functional fruit oil

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